Buffalo Bills vs. Los Angeles Chargers full preview: Prediction, picks, odds, props for NFL Week 16

The Buffalo Bills will face off against the Los Angeles Chargers in Week 16 of the NFL season at SoFi Stadium on Saturday, scheduled to commence at 8 p.m. EST.

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Bills vs. Chargers betting preview

This prediction for Saturdayโ€™s NFL matchup between the Bills and Chargers is from Dimers.com, a leader in sports betting predictions, along with our best bet of the game.

Utilize the interactive widget below to see the current spread, over/under, and moneyline betting odds and probabilities for the Bills-Chargers matchup at SoFi Stadium.

Check out all the important details on tonightโ€™s game, as well as the best odds sourced from the top sportsbooks in the country.

Game details

Key info for Bills vs. Chargers, including where the game is and what time it kicks off.

  • Teams: Buffalo Bills vs. Los Angeles Chargers
  • Date: Saturday, December 23, 2023
  • Kickoff: 8 p.m. EST
  • Location: SoFi Stadium

Odds

The latest and best odds for the NFL clash between the Bills and Chargers.

  • Spread: Bills -12.5 (-110), Chargers +12.5 (-110)
  • Moneyline: Bills -700, Chargers +560
  • Total: Over/Under 44 (-110/-110)

The odds and lines featured here are the best available from selected sports betting sites at the time of publication and are subject to change.

Expert prediction: Bills vs. Chargers

Using advanced data analysis and advanced algorithms, Dimers has executed 10,000 simulations of Saturdayโ€™s Bills vs. Chargers matchup.

According to Dimersโ€™…

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