Scientists have been in a race to find a “fountain of youth” pill that has the potential to increase longevity or reverse aging. Are we there yet? Looks like we are a step closer to the ever-elusive elixir of life.
In what could be a groundbreaking discovery, a group of researchers from Harvard has identified six chemical cocktails that they say can reverse the aging process in both human and mouse skin cells.
“Grateful to share our latest publication: We’ve previously shown age reversal is possible using gene therapy to turn on embryonic genes. Now we show it’s possible with chemical cocktails, a step towards affordable whole-body rejuvenation,” tweeted Dr. David Sinclair, a molecular biologist at Harvard Medical School and co-author of the study.
Grateful to share our latest publication: We’ve previously shown age reversal is possible using gene therapy to turn on embryonic genes. Now we show it’s possible with chemical cocktails, a step towards affordable whole-body rejuvenation 1/17 https://t.co/J9c01lv5FQ
— David Sinclair (@davidasinclair) July 12, 2023
“We identify six chemical cocktails, which, in less than a week and without compromising cellular identity, restore a youthful genome-wide transcript profile and reverse transcriptomic age. Thus, rejuvenation by age reversal can be achieved, not only by genetic, but also chemical means, ” the researchers wrote in the study published in the journal Aging.
The study evaluated the impact of a drug concoction that contains the growth hormone metformin and a drug that activates the enzyme-activated protein kinase (AMPK) in the rejuvenation of aged muscles, liver tissue and other organs.
“Studies on the optic nerve, brain tissue, kidney and muscle have shown promising results, with improved vision and extended lifespan in mice and, recently, in April of this year, improved vision in monkeys,” Dr. Sinclair said.
The team claimed they found age-reversing effects with all six combinations. The impact of a four-day…
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